In Ayurveda , Explanation of concepts like Granthi, Arbuda etc ,shows similarities with cancer. Both indicates unwanted growth of tissues in body. In the context of vrana(Ulcers) also we can observe symptoms resembles malignancy. According to Ayurveda (Ayurvedic Treatment for Cancer in Kerala, India) all diseases are caused due to imbalance of tridoshas.
Ayurveda explains arbuda results from lifestyle errors such as unhealthy foods, poor hygiene, or poor behaviour, or from physical trauma, all leading to imbalances of Vata, Pitta, and Kapha, Resulting in injury to the inner layer of skin and the formation of abnormal branches of blood vessels. Ashtanga hridaya describes that whenever there is excessive formation of Mamsa dhatu it may lead to various pathological conditions such as alaganda, Gandamala, Arbuda, Granthi and Adimamsa where all indicates excessive growth of tissues.
Granthi has been described as a round, hard, and bulging swelling produced due to vata and kapha aggravation vitiating the muscular tissue, blood, and fatty tissues.
Arbuda has been described as a round, large, muscular, immovable, deeply rooted, slowly growing swelling produced due to the aggravation of Doshas vitiating the muscle, blood, and fatty tissues.